Type 2 Diabetes Increases Risk for Dementia

Type 2 diabetes risk for dementia

People who are suffering from type 2 diabetes are at higher risk for developing dementia than those without diabetes. That’s according to a new study published in the journal by Diabetes Care.

The study authors also report that vascular dementia – a common type of dementia that affects blood flow to the brain due to the accumulation of bad eating habit and stress. People with type 2 diabetes brings more risk to women than men, according to a new study.


The most common cause of dementia is Alzheimer’s disease, which is non-vascular, said senior author Rachel R. Huxley of Curtin University in Perth, Australia.

Nonvascular dementia means it’s not related to problems with blood vessels.

“In Alzheimer’s disease, nerve cells throughout the brain die off, and abnormal proteins accumulate in the brain for reasons not entirely known,” Huxley said. “Vascular dementia, in contrast, is the result of impaired blood flow to the brain, usually by a series of small, imperceptible strokes.”

Type 2 Diabetes and Women

Diabetes in women seems to confer more risk for other conditions as well, Huxley said.

“These findings add to the evidence that diabetes confers a greater vascular hazard in women compared with men,” Huxley told Reuters Health by email. “Diabetes confers a greater risk of developing heart disease, stroke and now vascular dementia in women compared with men.”

The authors reviewed 14 studies involving a total of more than 2 million individuals, including more than 100,000 dementia patients. They reported their findings in Diabetes Care.

Overall, people with diabetes were 60 percent more likely to develop any dementia than people without diabetes.

It’s important to note that the published paper is based on observational studies, meaning the relationship could be due to other health issues such as obesity, smoking, an unbalanced diet and lack of exercise.

Women with diabetes were more than twice as likely as those without it to develop vascular dementia, compared to a smaller increase in risk for men with diabetes.

Their need to be more research into how sugar in the blood interacts with the blood vessels and whether that process is different in women in men, Huxley said.

Women tend to be undertreated for vascular risks relative to men, she noted.

“We can’t definitively say whether the relationship is causal or not because the studies were all observational (rather than randomized trials) and therefore there always remains the possibility that the relationship is confounded,” Huxley said.

A third factor, like obesity, could have been part of the relationship between diabetes and dementia, she said.

Keeping fit, maintaining a healthy diet, quitting smoking and giving your brain as well as your body regular work-outs can help decrease the risk of dementia for people with type 2 diabetes, Huxley said.


Source: Reuters

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